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KMID : 0191120120270080969
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Journal of Korean Medical Science
2012 Volume.27 No. 8 p.969 ~ p.971
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Clinical Factors Associated with Hepatitis A Virus Seropositivity in HIV-Infected Adults Living in a Country with an Epidemiologic Shift for Hepatitis A Virus Infection
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Baek Ji-Hyeon
Kim Chang-Oh
Park Jun-Yong
Jeong Su-Jin
Koo Nam-Soo
Kim Hye-Won
Han Sang-Hoon
Choi Jun-Yong
Song Young-Goo
Kim June-Myung
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Abstract
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The number of HIV-infected individuals susceptible to Hepatitis A virus (HAV) infection is increasing in Korea; however, it has proven difficult to devise a vaccination policy therefore because limited seroepidemiologic data exists for them. Accordingly, anti-HAV IgG was measured in 188 HIV-infected adults between July 2008 and July 2010. The nadir CD4+ T lymphocyte counts were not different between the HAV-positive and -negative groups (197 ± 138 vs 202 ± 129, P = 0.821). The only factor independently associated with seropositive status was age under 40 yr old (OR 0.017, P < 0.001). Our findings suggest that HAV vaccination in HIV-infected adults should be targeted at persons under the age of 40 yr
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KEYWORD
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HIV, HAV, Seropositivity
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